Translational Medicine Sr. Director
Enveda
United States · Remote
USD 300k-325k / year
Posted on Feb 11, 2026
Translational Medicine Sr. Director
Remote, United States
Clinical – Translational Medicine /
Full-time /
Remote
Let’s build the future of medicine - together.
Join Enveda as a Translational Medicine Sr. Director, ENV-308 in a remote capacity and help us transform natural compounds into life-changing medicines. We’re a team driven by curiosity and innovation - are you ready to make a difference?
Remote | Full-Time | $300,000-$325,000
What Makes Us Enveda
Life is smart, and we can learn from it. We’re reinventing drug discovery by harnessing nature’s intelligence. Our platform identifies new medicines four times faster than the industry standard because patients can’t wait. What sets Enveda apart isn’t just what we do - it’s how we do it. Our culture is built on creativity, collaboration, and deep respect for each other. We believe “People Create All Value,” and our success is driven by the extraordinary team turning our mission into reality every day.
Our Momentum
- Unicorn status: Achieved following a $150 million Series D funding round in 2025
- Discovery and innovation: Advanced our first drug candidate to Phase 1 trials in 2024
- Award-winning culture:
--Newsweek: Top 100 Global #MostLovedWorkplaces (2025)
--Forbes: America’s Best Startup Employers (2024 & 2025)
--Newsweek: America’s Greatest Startup Workplaces (2025)
--LinkedIn: Top Startups to Watch (2024)
These milestones reflect the impact of our team and we’re just getting started, but they’re only possible because of the diverse talent, perspectives, and relentless drive of our team, and people like you.
Your Role in Our Mission
At Enveda, every role drives impact. As a Translational Medicine Sr. Director, you’ll be at the forefront of delivering hope to patients everywhere. You will drive biomarker, MOA, and translational strategy for ENV-308, our lead metabolic program in chronic weight management. This role will serve as the connective tissue between preclinical biology, clinical development, and data interpretation, ensuring that human studies are mechanistically informed, biomarker-rich, supportive of commercial positioning, and decision-enabling.
The ideal candidate combines deep expertise in metabolic biology with practical experience translating hypotheses into clinical readouts and can move seamlessly between setting translational medicine strategy and hands-on execution.
As part of the ENV-308 Asset Team, you will report to the Asset Entrepreneur (Program Team Lead).
What You’ll Do
- Own End-to-End Translational Scope for ENV-308: Lead the translational strategy across preclinical and clinical development, with clear ownership for how human biology informs program direction, risk, and value.
- Define Biomarker & MOA Strategy: In collaboration with our MOA and pre-clinical teams, develop and prioritize biomarker and MOA hypotheses, including trial, experiment and assay design to support development decisions and differentiate ENV-308.
- Execute Translational Analyses: Take a hands-on role in analyzing and interpreting clinical, biomarker, and translational data in real time to guide active program decisions.
- Make High-Impact Scientific Judgments: Apply independent scientific judgment to translational decisions that shape the development path and differentiation strategy.
- Lead External Vendor Scientific Oversight: Evaluate, select, and scientifically guide translational and biomarker vendors from feasibility through data delivery.
- Create Decision-Enabling Readouts: Ensure biomarker and translational outputs are high-quality, interpretable, and designed to support clear program decisions.
- Integrate Data into Program and Regulatory Decisions: Synthesize translational and clinical evidence into go/no-go recommendations and contribute translational input to INDs, protocols, and internal reviews.
- Operate as an Asset-Embedded Program Leader: Work as a peer within the program leadership team, embedding translational thinking into clinical design, development sequencing, and portfolio trade-offs.
Who will thrive in this role?
- Ph.D., M.D., or equivalent advanced degree in pharmacology, biomedical sciences, or a related field.
- Minimum of 10 years of experience in translational medicine and / or biomarker strategy within the biotechnology or pharmaceutical industry.
- Minimum of 5 years focused on metabolism / metabolic disease programs with at least some experience in Obesity and Diabetes with a strong scientific grounding in energy balance, appetite regulation, and metabolic adaptation.
- Proven track record of successfully leading translational programs from discovery through clinical development.
- Deep understanding of PK/PD principles, biomarker development, and their application in drug development.
- Strong leadership skills with the ability to influence cross-functional teams and drive strategic initiatives.
- Excellent communication and interpersonal skills, with a demonstrated ability to present complex scientific concepts to diverse audiences.
- Experience with regulatory interactions and knowledge of the regulatory requirements for biomarkers and translational endpoints.
If you’re passionate about innovation and impact, we encourage you to apply even if you don’t meet every requirement.
Our Values: Curiosity | Agency | Journey | Charity | Unity
Benefits: 90% Medical, Dental, Vision | 401k Match | Flexible PTO | Adoption Assistance
Enveda is protecting Job Seekers:
We care deeply about creating a safe, respectful experience for every applicant, so we wanted to share a few guidelines to help you spot anything that doesn’t feel right.
--You’ll always meet real Enveda team members through video or in-person conversations before receiving an offer.
--All communication from us will come from an @enveda.com or @envedabio.com email address.
--We’ll never ask you to purchase equipment, send money, or share sensitive banking details as part of any step in our recruiting process.
If something feels off or you’re unsure whether a message is truly from Enveda, please reach out at anytime at [email protected].
At Enveda, we’re building a place where everyone can do the best work of their life. We are an equal opportunity employer and value diversity in all its forms. Apply now and join a team committed to shaping the future of drug discovery.